In the world of electronics, Electrostatic Discharge (ESD) remains one of the most significant threats to device reliability and performance. The USBLC6-2P6 is a highly efficient ESD protection diode that plays a crucial role in safeguarding sensitive electronic circuits. This article explores the application and optimization design of the USBLC6-2P6 in ESD protection circuits, highlighting its advantages, features, and the best practices for integrating it into modern electronic systems.